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Non sedating muscle

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During the ten-day study period, the combined treatment group demonstrated significantly superior improvements in global ratings on day four, but not on day two or seven.

This study suggested some effectiveness of combined analgesic and muscle relaxant therapy when utilized early in the initial week of pain onset.

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The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics.The results of this study suggest that the effects of carisoprodol are not secondary to its sedative effects alone.In 1989, Basmajian compared the effectiveness of cyclobenzaprine (Flexeril) alone with diflunisal (Dolobid), placebo, and a combination of cyclobenzaprine and diflunisal in the treatment of acute low back pain and spasm.Results are expected by the fourth quarter of this year.In addition, the broad clinical experience and patient usage with this compound outside of the United States suggests low clinical development and regulatory risk, said Judy Caron, Ph D., Neuranas Chief Operating Officer and Head of Clinical Development.The muscle relaxing properties of muscle relaxants arise not from direct activity at the muscular or neuromuscular junction level but rather from an inhibition of more central polysynaptic neuronal (nerve cells that end in synapses) events.